天津中医药2016，Vol.33Issue(3)：135-138,4.DOI:10.11656/j.issn.1672-1519.2016.03.03
基于有序数据Meta分析模型评价针灸疗效及干预层次的研究:原发性抑郁症
Study to evaluate effficacy, intervention-level of acupuncture therapy based on Meta-analysis of ordinal data:major depressive disorder
摘要
Abstract
[Objective] Based on high quality data clinical evidence and Meta-analysis of ordinal data model to evaluate the efficacy, in-tervention-level of acupuncture treatment of major depressive disorder (MD-D). [Methods] The published papers on clinical trails for acupuncture treatment of MD-D were widely retrieved from Chinese and abroad Database. Quality of clinical evidence was evaluated by Jadad scale. Using the maximum likelihood method to fit the cumulative odds model, STATA12.0 software was used for data analyses. [Results] The 13 studies accord with the inclusive criterion were retrieved. Meta-analyses of ordinal data showed acupuncture compare with SSRIs increase the possibility of efficacy an increase of more than one level of 55%;acupuncture with SSRIs increase the possibility of efficacy an increase of more than one level of 183%. [Conclusion] According to the present stage clinical evidences, treatment mild and moderate MD-D acupuncture can be used as the main treatment method, with antidepressants can significantly improve the overall efficacy.关键词
针灸/原发性抑郁症/有序数据/Meta分析/疗效评价/干预层次Key words
acupuncture/major depressive disorder/ordinal data/Meta-analysis/efficacy/intervention-level分类
医药卫生引用本文复制引用
黎波,杜元灏,刘强..基于有序数据Meta分析模型评价针灸疗效及干预层次的研究:原发性抑郁症[J].天津中医药,2016,33(3):135-138,4.基金项目
国家自然科学基金项目(81403454). （81403454）
