现代妇产科进展2016，Vol.25Issue(3)：192-194,3.DOI:10.13283/j.cnki.xdfckjz.2016.03.007
复发性流产患者NK细胞毒性和子宫动脉血流灌注对妊娠结局的影响
Effects of the NK cytotoxicities and uterine artery flow on the pregnancy outcomes in pa-tients with the recurrent pregnancy losses
摘要
Abstract
Objective:To study the effect of the NK cytotoxicities and uterine artery flow on the pregnancy outcomes in patients with recurrent pregnancy losses ( RPL) . Methods:The NK cytotoxicities and uterine radial artery resistance index ( U-RI ) were analyzed retro-spectively in 162 RPL patients (abortion group,n=30 and delivery group,n=132). Results:Progestational NK toxicities were higher in abortion group than delivery group (P=0. 02),how-ever U-RIs were found no significantly differences between two groups ( P=0 . 12 ) . During the first trimester,NK cytotoxicities were higher in abortion group than delivery group,but there was no significant differences ( P>0 . 05 ) . U-RIs were decreased significantly as compared to non-pregnant period(P<0. 001),and along with the increase of pregnant time. Compared to the de-livery group,the U-RIs of the abortion group were significantly higher in the 7th,8th,9th week of the gestation(P=0. 008,P=0. 001,P=0. 043). Conclusions:The RPL patients,with high level of NK cytotoxicities before pregnancy and increased U-RIs in the 7th,8th,9th week of the gestation,would have a high risk of miscarriage again.关键词
复发性流产/子宫动脉血流阻力指数/自然杀伤细胞Key words
Recurrent pregnancy loss/Uterine radial artery resistance index/Natural killer cell分类
临床医学引用本文复制引用
颜妍,屠韡燕,王磊,王柳柳,鲍时华,Joanne Kwak-Kim..复发性流产患者NK细胞毒性和子宫动脉血流灌注对妊娠结局的影响[J].现代妇产科进展,2016,25(3):192-194,3.基金项目
2014年度上海市市级医院新兴前沿技术联合攻关项目(No:SHDC12014129) （No:SHDC12014129）
2014年度上海市医学引导类科技项目(No:14411966600) （No:14411966600）
