摘要
Abstract
Objective To explore the changes of red cell distribution width ( RDW) in patients with chronic obstruc-tive pulmonary disease ( COPD) at different levels and its significance.Methods From January 2013 to January 2015, 80 patients with COPD in Panzhihua City, Sichuan Province were divided into group A (grade 0), group B (gradeⅠ), group C ( gradeⅡ) and group D ( gradeⅢ) .Compared the four groups of patients'RDW, hemoglobin ( Hb) , red blood cell count ( RBC) , white blood cell count ( WBC) , brain natriuretic peptide ( BNP) , C-reactive protein ( CRP) and carbon dioxide into pressure ( PaCO2 ) oxygen partial pressure ( PaO2 ) , and factors related to the gradeⅢpatients with chronic obstructive pul-monary disease (COPD).Results The 4 groups had no statistically significant difference of Hb and RBC ( P >0.05). RDW, WBC, BNP, CRP and PaCO2 in the order of group D >group C >group B>group A, Level of PaO2 in the order of group A >group B >group C >group D, the difference has statistical significance ( P <0.05).ClassⅢchronic obstruc-tive pulmonary disease ( COPD) patients'RDW and oxygen points pressure was negative correlated ( r =-0.395, P <0.01), and BNP and CRP were positively correlated ( r =0.783, r =0.362, P <0.05).Conclusion It proved that the COPD patient's RDW and PaO2 showed negative correlation, and can better reflect the patient's inflammatory reaction level, it can be used as severity index for patients with COPD.关键词
慢性阻塞性肺疾病/呼吸衰竭/红细胞分布宽度/炎性反应Key words
Chronic obstructive pulmonary disease/Respiratory failure/Red cell distribution width/Inflammatory re-sponse
