中国感染控制杂志2016，Vol.15Issue(3)：176-178,3.DOI:10.3969/j.issn.1671-9638.2016.03.008
综合干预措施对 ICU 患者呼吸道多重耐药菌感染／定植的防控效果
Effect of comprehensive intervention measures on preventing and controlling multidrug-resistant organism infection/colonization in respiratory tract of intensive care unit patients
摘要
Abstract
Objective To evaluate the effect of comprehensive intervention measures on preventing and controlling the infection/colonization of multidrug-resistant organism(MDRO)in respiratory tract of intensive care unit(ICU) patients.Methods Throat swabs and sputum specimens from artificial airway suction were taken for bacterial cul-ture and antimicrobial susceptibility testing at the first,fourth,eighth day,and then every seven day of patients’ admission.June-December 2013 was as pre-intervention group,from January 2014,comprehensive intervention measures began to be implemented,June-December 2014 was as post-intervention group,detection of MDROs were analyzed statistically.Results A total of 253 isolates of MDROs were detected,before and after intervention were 164 and 89 isolates respectively,191 isolates(75.49%)were carbapenem-resistant Acinetobacterbaumannii strains,before and after intervention were 119 and 72 isolates respectively.Incidence of MDRO respiratory tract infection before and after interven-tion were 52.94% and 30.43% respectively,difference was significant(χ2 =5.02,P =0.03).The average hospitalization time of patients in pre-and post-intervention groups were (8.07±2.52)days and (6.89±1.71)days respectively,differ-ence was significant (t=5.40,P <0.01).Conclusion MDROs are major pathogens causing healthcare-associated infection (HAI)in ICU patients,comprehensive intervention measures can reduce the occurrence of HAI.关键词
重症监护病房/多重耐药菌/干预措施/感染/定植/医院感染Key words
intensive care unit/multidrug-resistant organism/intervention measure/infection/colonization/healthcare-associated infection分类
医药卫生引用本文复制引用
梅雪飞,荚恒敏,张亮,杨会志,范恒梅,谢少清..综合干预措施对 ICU 患者呼吸道多重耐药菌感染／定植的防控效果[J].中国感染控制杂志,2016,15(3):176-178,3.基金项目
2012年安徽医科大学科学研究基金项目 （）
