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靶向口服抗凝药给华法林带来的新思路

况赟 赖青 杨双 龚丽英 项玉霞 李静乐 阳国平

中国临床药理学杂志2016,Vol.32Issue(5):473-475,3.
中国临床药理学杂志2016,Vol.32Issue(5):473-475,3.DOI:10.13699/j.cnki.1001-6821.2016.05.028

靶向口服抗凝药给华法林带来的新思路

New challenge of target-specific anticoagulants replacing warfarin

况赟 1赖青 2杨双 1龚丽英 3项玉霞 3李静乐 3阳国平3

作者信息

  • 1. 中南大学 药学院,长沙 410013
  • 2. 中南大学 湘雅三医院 临床药理中心,长沙410013
  • 3. 中南大学 湘雅三医院 临床药理中心,长沙410013
  • 折叠

摘要

Abstract

Warfarin was the only oral anticoagulant drug , widely used in the prevention of thromboembolism events.The antithrombotic effect of warfarin has been very clear , but there are also some defects , such as that the treatment window is narrow and individual difference is very big.In recent years , the emergence of new targeted oral anticoagulant agents has provided a new choice for the anticoagulant drugs.The development of targeted oral anticoagulant drugs is reviewed , and the new challenge to warfarin is discussed.

关键词

靶向口服抗凝药/华法林/心房颤动/深静脉血栓

Key words

targeted oral anticoagulant drug/warfarin/atrial fibrilla-tion/deep venous thrombosis

分类

药学

引用本文复制引用

况赟,赖青,杨双,龚丽英,项玉霞,李静乐,阳国平..靶向口服抗凝药给华法林带来的新思路[J].中国临床药理学杂志,2016,32(5):473-475,3.

基金项目

国家自然科学基金资助项目(81373476);科技部国际科技合作与交流专项基金资助项目 ()

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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