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超声辅助响应面法优化巫山淫羊藿中朝藿定 C和淫羊藿苷共同提取工艺研究

张建海 冯彬彬 牛小花

中国中医药信息杂志2016,Vol.23Issue(3):85-88,4.
中国中医药信息杂志2016,Vol.23Issue(3):85-88,4.DOI:10.3969/j.issn.1005-5304.2016.03.023

超声辅助响应面法优化巫山淫羊藿中朝藿定 C和淫羊藿苷共同提取工艺研究

Optimization of Ultrasonic-Assisted Extraction of Epimedin C and Icariin from Epimedii Wushanensis Herba by Using Response Surface Methodology

张建海 1冯彬彬 2牛小花2

作者信息

  • 1. 重庆三峡医药高等专科学校中药研究所,重庆 404120
  • 2. 重庆三峡医药高等专科学校药学系,重庆 404120
  • 折叠

摘要

Abstract

Objective To optimize ultrasonic-assisted extraction Epimedin C and Icariin from Epimedii Wushanensis Herba by response surface methodology. Methods On the basis of single factor tests, Box-Behnken experimental design and response surface methodology were adopted to optimize extraction conditions with the concentration of ethanol, ultrasonic time and solid-liquid ratio as factors. HPLC was used to determine the content of Epimedin C and Icariin from Epimedii Wushanensis Herba. Results Optimal ultrasound-assisted extraction technology was as following: the concentration of ethanol was 73%; the ultrasonic time was 22 min; the ratio of liquid to material was 1:32. The contents of Epimedin C and Icariin from Epimedii Wushanensis Herba were 15.90% and 0.75%, respectively. Conclusion This extraction technology can improve the extraction efficiency of Epimedin C and Icariin from Epimedii Wushanensis Herba, which is in accordance with predicted value.

关键词

巫山淫羊藿/朝藿定 C/淫羊藿苷/超声辅助提取/响应面法

Key words

Epimedii Wushanensis Herba/Epimedin C/Icariin/ultrasound-assisted extraction/response surface method

分类

医药卫生

引用本文复制引用

张建海,冯彬彬,牛小花..超声辅助响应面法优化巫山淫羊藿中朝藿定 C和淫羊藿苷共同提取工艺研究[J].中国中医药信息杂志,2016,23(3):85-88,4.

基金项目

重庆市教委自然科学项目 ()

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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