中国中医药信息杂志2016，Vol.23Issue(4)：12-15,4.DOI:10.3969/j.issn.1005-5304.2016.04.004
头痛宁方治疗偏头痛临床研究
Clinical Study onToutongning Formula in Treatment of Migraine
摘要
Abstract
Objective To observe the clinical efficacy ofToutongning Formula in the treatment of migraine. Methods Totally 100 cases of migraine patients (wind disturbance, blood stasis syndrome) were randomly divided into two groups. Patients in the experimental group were treated withToutongning Formula orally, and patients in the control group were treated with flunarizine capsules 5 mg orally, for 30 d. The scores of number, degree, duration and accompanying symptoms of episodes before and after treatment were observed, the total scores were calculated, and adverse reactions were recorded, to evaluate the clinical efficacy and safety.Results Clinical total efficiency was 92.0% (46/50) in experimental group and 64.0% (32/50) in the control group; the incidence rate of adverse reactions was 20.0% (10/50) in experimental group and 80.0% (40/50) in the control group; there was statistical significant differences in efficacy and adverse reactions between the two groups (P<0.05). After the treatment, the differences in the scores of number, degree, duration and accompanying symptoms of episodes, and in the total scores between the two groups was statistically significant (P<0.05). There was statistical significance in the different value of above indexes before and after treatment between the two groups (P<0.05).ConclusionToutongning Formula can not only improve symptoms significantly in patients with migraine (wind disturbance, blood stasis syndrome), but also reduce adverse reactions, with more safety and efficacy than flunarizine capsules.关键词
头痛宁方/偏头痛/氟桂利嗪/临床研究Key words
ToutongningFormula/migraine/flunarizine/clinical study分类
医药卫生引用本文复制引用
任珊,陈志刚..头痛宁方治疗偏头痛临床研究[J].中国中医药信息杂志,2016,23(4):12-15,4.基金项目
北京中医药大学“重点学科”开放课题 （）
