中国中医药信息杂志2016，Vol.23Issue(4)：76-79,4.DOI:10.3969/j.issn.1005-5304.2016.04.020
响应面法优化川楝子总黄酮的提取工艺
Optimization of Extraction Process of Flavonoids from Toosendan Fructus by Response Surface Methodology
摘要
Abstract
Objective To optimize extraction process of flavonoids from Toosendan Fructus.Methods Three parameters that significantly affect the extraction rate of flavonoids, ratio of material to water, extraction time and ethanol concentration, were taken into consideration for extraction ratio of flavonoids from Toosendan Fructus. Based on the results of single-factor experiment, the extraction parameters of flavonoids from Toosendan Fructus were optimized by Box-Behnken of response surface methodology (RSM).Results The optimum extraction conditions were as follow: material to water ratio was 1:35; extraction time should be 3 h; ethanol concentration was 70%. The extraction ratio was up to 0.587 3% in the optimum extraction conditions.Conclusion The actual value is highly matching the theoretically value of RSM model. The results indicated that this method can rationally optimize extraction process of flavonoids from Toosendan Fructus.关键词
川楝子/总黄酮/响应面法/提取工艺Key words
Toosendan Fructus/flavonoids/response surface methodology/extraction process分类
医药卫生引用本文复制引用
田永芝,王亚丽,孙茹,赵婧,刘群,王晨晓,马艳,蔡梅超..响应面法优化川楝子总黄酮的提取工艺[J].中国中医药信息杂志,2016,23(4):76-79,4.基金项目
山东省中医药科技发展计划项目（2011-016）；山东中医药大学SRT项目 （）
