中国中医药信息杂志2016，Vol.23Issue(4)：83-86,4.DOI:10.3969/j.issn.1005-5304.2016.04.022
新疆阿魏乙酸乙酯部位质量控制方法研究
Study on Quality Control of Ethyl-acetate Parts ofFerula Sinkiangensis
摘要
Abstract
Objective To establish the method for quality control of ethyl-acetate parts of Ferula sinkiangesis. Methods HPLC was used to detect the contents of ferulic acid, farnesiferol A and farnesiferol C. Waters XTerra RPC18 column (250 mm×4.6 mm, 5 µm) was used; acetonitrile-0.1% phosphoric acid was as mobile phase with gradient elution; flow rate was 1.0 mL/min; detective wavelength was 324 nm; temperature was 30℃; sample volume was 10 µL ResultsFerulic acid, farnesiferol A, and farnesiferol C showed a good linear relationship range from 0.05– 1.0 mg/mL, 0.132–2.64 mg/mL, and 0.118–2.36 mg/mL, respectively. The average recovery rates were 99.34%, 98.96% and 99.24% respectively. The contents of ferulic acid, farnesiferol A and farnesiferol C were 33.4, 76.5, 72.3 mg/g respectively.Conclusion The method was simple, accurate and repeatable, with good repeatability and stability, which can be used for the quality control of ethyl-acetate parts ofFerula sinkiangesis.关键词
新疆阿魏/乙酸乙酯部位/阿魏酸/法尼斯淝醇A/法尼斯淝醇C/质量控制Key words
Ferula sinkiangesis/ethyl-acetate part/ferulic acid/farnesiferol A/farnesiferol C/quality control分类
医药卫生引用本文复制引用
张海英,李伟,周龙龙,姜林,周铭心..新疆阿魏乙酸乙酯部位质量控制方法研究[J].中国中医药信息杂志,2016,23(4):83-86,4.基金项目
国家自然科学基金 （）
