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多指标综合评分法优选三拗汤提取工艺研究

张金花 刘陶世 程建明 毕肖林 钱海峰 陈冬冬

中国中医药信息杂志2016,Vol.23Issue(4):91-94,4.
中国中医药信息杂志2016,Vol.23Issue(4):91-94,4.DOI:10.3969/j.issn.1005-5304.2016.04.024

多指标综合评分法优选三拗汤提取工艺研究

Study on Extracting Process ofSan Ao Decoction by Multi-indexes Grading Method

张金花 1刘陶世 1程建明 1毕肖林 1钱海峰 1陈冬冬1

作者信息

  • 1. 南京中医药大学药学院,江苏南京 210046
  • 折叠

摘要

Abstract

Objective To simultaneously determinate the contents of four active ingredients (Ephedrine Hydrochloride, Pseudoephedrine Hydrochloride, Amygdalin and Glycyrrhizinate) ofSan Ao Decoction by HPLC; To optimize the extracting process ofSan Ao Decoction.Methods The orthogonal test was employed. Volume of water, time of extraction and times of extraction were set as investigation factors; the transport rates of Ephedrine Hydrochloride, Pseudoephedrine Hydrochloride, Amygdalin and Glycyrrhizinate and the extraction rates were set as investigation indexes to conduct multi-indexes grading.Results The influence factors of the extraction ofSao Ao Decoction were the times of extraction > decoction time > the volume of water. The best extraction condition was: ten fold water; extract for three times; 1 h for each time.Conclusion The optimized extraction process is stable and feasible.

关键词

三拗汤/正交试验/提取工艺

Key words

San Ao Decoction/orthogonal test/extracting process

分类

医药卫生

引用本文复制引用

张金花,刘陶世,程建明,毕肖林,钱海峰,陈冬冬..多指标综合评分法优选三拗汤提取工艺研究[J].中国中医药信息杂志,2016,23(4):91-94,4.

基金项目

国家自然科学基金(81403114);江苏高校优势学科建设工程资助项目 ()

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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