中国中医药信息杂志2016，Vol.23Issue(4)：98-101,4.DOI:10.3969/j.issn.1005-5304.2016.04.026
壳聚糖絮凝法精制补肾养血颗粒水提液的工艺研究
Study on Refining Water Extract ofBushen Yangxue Granules by Chitosan Flocculation
摘要
Abstract
Objective To optimize refinement of water extract from Bushen Yangxue Granules by chitosan flocculation.Methods According to the content of icariin detected by HPLC, the waters amount, extraction time and extraction times were evaluated by orthogonal design. The effects of the solution concentration, clarifying temperature and the amount of clarifying agent on the flocculation clarification processes were optimized with the content of icariin and polysaccharides.Results The optimum water extraction processes A2B1C3 were follows: 10 times amount of water, three times extraction and 1 h for each extraction process. The optimized flocculation clarification processes A1B2C3 were as follows: solution concentration was 0.4 g/mL, the clarifying temperature was 40℃ and the addition of chitosan was 0.1%.Conclusion The optimized refining process is stable and feasible.关键词
补肾养血颗粒/淫羊藿苷/壳聚糖/精制工艺/正交试验Key words
Bushen Yangxue Granules/icariin/chitosan/refining process/orthogonal test分类
医药卫生引用本文复制引用
杜艳娇,康琛,杜茂波,沈硕,李曼玲,梁丽娜,刘淑芝..壳聚糖絮凝法精制补肾养血颗粒水提液的工艺研究[J].中国中医药信息杂志,2016,23(4):98-101,4.基金项目
北京市中医药科技发展项目 （）
