质谱学报2016，Vol.37Issue(2)：114-120,7.DOI:10.7538/zpxb.2016.37.02.0114
电喷雾萃取电离质谱在线检测卷烟主流烟气
Online Analysis of Mainstream Cigarette Smoke by Extractive Electrospray Ionization Mass Spectrometry
摘要
Abstract
Mainstream cigarette smoke (MCS)is very complex and highly dynamic aero-sol.Some substances in smoke are highly reactive,resulting in a continuously changing mixture during smoke processing of trapping and separation.Because the conventional off-line methods can alter the smoke composition,an online method of extractive elec-trospray ionization mass spectrometry (EESI-MS)was established for analyzing of MCS.The MCS,generated by a single channel smoking machine,was directly intro-duced into EESI-MS without sample preparation,and the mass spectrum was obtained. MS was operated at collision induced dissociation (CID)mode for qualitative analysis of nicotine.This method was applied for the MCS monitoring on a puff-by-puff basis,and the results showed that the signal intensity of total ions (m/z 50-400 )and ion of nicotine (m/z 1 63)increased with puffs,which indicated the trend of MCS emissions with the length of cigarette.Then,EESI-MS was used for analyzing of MCS of various cigarette brands.The result of principal component analysis (PCA)indicated that the EESI-MS method could be applied to differentiate MCS of various cigarette brands,the clustering analysis showed that the EESI-MS method could be applied to cluster the MCS of various cigarette brands and measure their similarity.关键词
电喷雾萃取电离源(EESI)/卷烟主流烟气/烟碱/主成分分析(PCA)/聚类分析Key words
extractive electrospray ionization (EESI)/mainstream cigarette smoke (MCS)/nicotine/principal component analysis (PCA)/clustering analysis分类
化学化工引用本文复制引用
崔华鹏,于永杰,陈黎,樊美娟,谢复炜,张兴磊,刘坤..电喷雾萃取电离质谱在线检测卷烟主流烟气[J].质谱学报,2016,37(2):114-120,7.基金项目
郑州烟草研究院院长科技发展基金项目(322013CA0300)资助 （322013CA0300）
