重庆医学2016，Vol.45Issue(7)：903-904,908,3.DOI:10.3969/j.issn.1671-8348.2016.07.012
淋巴细胞亚群及血细胞抗体检测在再生障碍性贫血中的临床意义
Clinical significance of detecting lymphocyte subsets and hematocyte antibody in aplastic anemia
高泽莉 1汪宏云 1叶梅 1李莉 1周丽 1郭峰1
作者信息
- 1. 四川省攀枝花学院附属医院血液科 617000
- 折叠
摘要
Abstract
Objective To investigate of the change of peripheral blood lymphocyte subsets and blood cell antibodies in aplas‐tic anemia and its clinical significance .Methods The lymphocyte subsets CD3+ ,CD3+ CD4+ ,CD3+ CD8+ ,CD4+ /CD8+ ,CD3-CD19+ ,CD3-CD16+CD56+ from 25 aplastic anemia(including SAA 7 cases ,NSAA18 cases) ,and hematocyte antibody detection (granulocyte ,erythrocyte ,platelet cytomembrane) and 20 controls were examined by flow cytometry .Results CD4+ T lymphocyte percentage ,CD4/CD8 ratio ,the percentage of CD56+ in aplastic anemia patients significantly decreased(P<0 .05) .Blood cell anti‐bodies (platelet antibody ,erythrocyte antibody ,granulocyte antibody) were significantly higher than the control group (P<0 .05) . Conclusion Aplastic anemia cellular immune function in patients is abnormal ,and antibody positive rate is high ,and it prompt that humoral immunity is also abnormal .关键词
再生障碍性贫血/淋巴细胞亚群/血细胞抗体Key words
anemia aplastic/lymphocyte subsets/hematocyte antibody分类
医药卫生引用本文复制引用
高泽莉,汪宏云,叶梅,李莉,周丽,郭峰..淋巴细胞亚群及血细胞抗体检测在再生障碍性贫血中的临床意义[J].重庆医学,2016,45(7):903-904,908,3.
