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HIV/AIDS合并HBV/HCV感染病毒载量水平及与T淋巴细胞相关性的探讨

张茹薏 游晶 杨微波 饶少锋

重庆医学2016,Vol.45Issue(7):912-914,3.
重庆医学2016,Vol.45Issue(7):912-914,3.DOI:10.3969/j.issn.1671-8348.2016.07.015

HIV/AIDS合并HBV/HCV感染病毒载量水平及与T淋巴细胞相关性的探讨

Discussing viral load levels after HIV/AIDS merges HBV/HCV infection and its relationship with T lymphocytes

张茹薏 1游晶 1杨微波 1饶少锋1

作者信息

  • 1. 昆明医科大学第一附属医院感染性疾病科 650032
  • 折叠

摘要

Abstract

Objective To explore the viral load levels after HIV/AIDS merges HBV/HCV infection and its relationship with T lymphocytes .Methods HIV RNA ,HBV DNA ,HCV RNA ,CD4+ T lymphocyte frequency ,CD8+ T lymphocyte frequency ,CD4/CD8 measured in HIV/AIDS simple infection group ,mixed HIV/HBV infection group and mixed HIV/HCV infection group .Ana‐lyze relationship of T lymphocyte and HIV RNA ,the correlation of HBV DNA/HCV RNA ,HIV RNA ,CD4+ T lymphocyte fre‐quency ,CD8+ T lymphocyte frequency ,CD4/CD8 .Results CD4+ T lymphocyte frequency of HIV/AIDS simple infection group , mixed HIV/HBV infection group and mixed HIV/HCV infection group showed negative correlated with their respective group′s HIV RNA(P<0 .05);CD8+ T lymphocyte frequency of HIV/AIDS simple infection group and mixed HIV/HBV infection group showed negative correlated with their respective group′s HIV RNA(P<0 .05);CD4/CD8 of HIV/AIDS simple infection group , mixed HIV/HBV infection group and mixed HIV/HCV infection group show negative correlated with their respective group′s HIV RNA(P<0 .05) .Conclusion T lymphocyte of HIV/AIDS patients drop faster ,leading to high viral load of HIV RNA ,HBV DNA and accelerating HIV disease progress with HBV infection .T lymphocyte of HIV/AIDS patients with HBV infection drop faster than with HCV infection .

关键词

肝炎病毒 ,乙型/肝炎病毒 ,丙型/HIV/AIDS/HIV RNA/T淋巴细胞

Key words

hepatitis B virus/hepatitis C virus/HIV/AIDS/HIV RNA/T lymphocyte

分类

医药卫生

引用本文复制引用

张茹薏,游晶,杨微波,饶少锋..HIV/AIDS合并HBV/HCV感染病毒载量水平及与T淋巴细胞相关性的探讨[J].重庆医学,2016,45(7):912-914,3.

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