重庆医学2016，Vol.45Issue(8)：1034-1036,3.DOI:10.3969/j.issn.1671-8348.2016.08.009
右美托咪定术前滴鼻在小儿腹股沟疝手术中的应用
Effects of preoperative intranasal dexmedetomidine in children inguinal hernia operation
摘要
Abstract
Objective To observe the clinical effect of preoperative intranasal dexmedetomidine on sedation and preventing postoperative agitation in children inguinal hernia operation .Methods Forty children patients ,aged 1-s5 years old ,ASA Ⅰ ,were selected and equally randomized into 2 groups ,receiving intranasally dexmedetomidine 1 μg/kg(group Dex) and the same volume of normal saline (group NS) at preoperative 30 min respectively .The sedation score ,emotion score when separating from their par‐ents ,mask inhalation induction resistance score were evaluated at 30 min after medication ,furthermore the agitation scores were ob‐served and recorded at postoperative 30 min ,1 ,2 h .Results The sedation score ,emotion score when separating from their parents and mask inhalation induction resistance score in the Dex group were superior to the NS group ,moreover the agitation score at each points were lower than those in the NS group(P<0 .05) .Conclusion Preoperative intranasal dexmedetomidine can be safely used in children inguinal hernia operation ,has better sedative effect ,meanw hile reduces the postoperative agitation occurrence .关键词
右美托咪定/术前用药 ,滴鼻/儿童Key words
dexmedetomidine/premedication ,intranasal/children分类
医药卫生引用本文复制引用
岳冬梅,刘苏,张月英,齐敦益..右美托咪定术前滴鼻在小儿腹股沟疝手术中的应用[J].重庆医学,2016,45(8):1034-1036,3.基金项目
国家自然科学基金资助项目（81371242）。 （）
