国际医学放射学杂志2016，Vol.39Issue(2)：116-119,4.DOI:10.19300/j.2016.L3674
18F-FDG PET/CT在行结肠癌检查时发现 同时性重复癌的价值
The value of 18F-FDG PET/CT in detecting synchronous primary malignant neoplasms in patients with colon cancer
摘要
Abstract
Objective To investigate the value of 18F-FDG PET/CT in detecting synchronous primary malignant neoplasms in patients with colon cancer. Methods 232 cases with pathology-proven colon cancer who underwent 18F-FDG PET/CT imaging were retrospectively evaluated in the study. By comparing with the pathological diagnosis with chi square test and the kappa coefficient test, the diagnostic efficacy of PET/CT imaging for synchronous primary malignant neoplasms was analyzed. Results Among 232 cases with histologically confirmed colon cancer, there were 56 cases were pathologically diagnosed as synchronous primary malignant neoplasms. Fifty-three cases were true positive cases diagnosed by 18F-FDG PET/CT. There was 4 false positive cases, of which 1 case was polyps, 1 case was adenoma (precancerous lesions), 1 case was thyroid adenoma, and one was pulmonary inflammatory pseudotumor. There were 3 false negative cases, including 1 case of gastric antrum ring cell carcinoma, 1 case of renal clear cell carcinoma, and 1 case of primary hepatocellular carcinoma which was diagnosed as colon cancer liver metastasis by 18F-FDG PET/CT imaging. The sensitivity, specificity, and accuracy of 18F-FDG PET/CT imaging were 94.64%, 97.58%, and 96.83%respectively. There was no statistically significant difference between pathological and PET/CT diagnosis (P≈1.000), and showed high consistency between the two diagnostic methods (kappa value 0.917, P=0.000). Conclusion 18F-FDG PET/CT can effectively detect unexpected synchronous primary malignant neoplasms in patients with colon cancer.关键词
结肠癌/重复癌/正电子发射体层成像/体层摄影术,X线计算机Key words
Colon carcinoma/Synchronous malignant neoplasms/PET/Tomography/X-ray computed引用本文复制引用
朱湘,宋秀宇,王健,徐文贵..18F-FDG PET/CT在行结肠癌检查时发现 同时性重复癌的价值[J].国际医学放射学杂志,2016,39(2):116-119,4.基金项目
国家科技重大项目(2013ZX09303001) （2013ZX09303001）
