四川医学2016,Vol.37Issue(3):296-298,3.DOI:10.16252/j.cnki.issn1004-0501-2016.03.019
原发性三叉神经痛伽玛刀治疗(附838例分析)
Gamma Knife Treatment for Primary Trigeminal Neuralgia
吴高峰 1雷进 1吴娜娜 2廖述才1
作者信息
- 1. 成都363医院,四川 成都610041
- 2. 成都市第一人民医院,四川 成都610041
- 折叠
摘要
Abstract
Objective To evaluate the efficacy of gamma knife in the treatment of primary trigeminal neuralgia and its re-lated factors. Methods We use 1. 5T magnetic resonance imaging,Gamma-TPS treatment planning system treated 838 cases of primary trigeminal neuralgia. The therapeutic targets were at the zone where the sensory root of the trigeminal nerve enters pons ( REZ) ,and with 4 mm collimator,the maximum central dose was 70~90 Gray. We cover the targets with 50% isodose curve and the dose at brainstem margin was 15~16Gy. Results 586 cases were followed up for 3 to 48 months,among which there were 410 patients(70%)with complete pain relief(70%),59 patients(10%)whose pain basically disappeared(relieved more than 80%),83 patients(14. 2%)whose pain relieved more than 50% and 34 patients(5. 8%)receiving no effect. The total effective rate was 94. 2%,while 23 petients(3. 9%)had transient mild facial numbness and hypoesthesia,but no other complications. Con-clusion Gamma knife,in the treatment of primary trigeminal neuralgia,is significant and safe as an ideal therapeutic method.关键词
原发性三叉神经痛/伽玛刀/三叉神经感觉根Key words
primary trigeminal neuralgia/gamma knife/sensory root of trigeminal nerve分类
医药卫生引用本文复制引用
吴高峰,雷进,吴娜娜,廖述才..原发性三叉神经痛伽玛刀治疗(附838例分析)[J].四川医学,2016,37(3):296-298,3.