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肝硬化食管胃静脉曲张破裂出血相关危险因素分析

黄鹤 伦伟健 梁晓燕 刘浏 贾柳萍

四川医学2016,Vol.37Issue(3):320-323,4.
四川医学2016,Vol.37Issue(3):320-323,4.DOI:10.16252/j.cnki.issn1004-0501-2016.03.027

肝硬化食管胃静脉曲张破裂出血相关危险因素分析

The Analysis of Risk Factors in Esophageal Varices Bleeding of Cirrhosis Patients

黄鹤 1伦伟健 1梁晓燕 1刘浏 1贾柳萍1

作者信息

  • 1. 南方医科大学附属南海医院消化内科,广东 佛山528200
  • 折叠

摘要

Abstract

Objective To discuss predictor of esophageal varices bleeding of cirrhosis patients in order to provide refer-ence for clinic. Methods 479 patients treated in our hospital with cirrhosis united esophageal varices bleeding from 2010. 01 to 2015. 04 were collected as bleeding group and 672 patients treated at the same time with cirrhosis but no esophageal varices bleed-ing as control group. Analyze the medical data of the two groups statistically. Results The difference of ages,sex and cases of dis-ease has no statistic significance(P>0. 05),the serum total bilirubin;activated partial prothrombin time(APPT),portal hyperten-sive gastric disease and combined peptic ulcer has no statistic significance(P>0. 05). Liver function child-pigh score,grading of esophageal varices,medium granular cell,main diameter of portal vein,main diameter of splenic vein,ascites ratio,spleen thickness and RC sign ratio of the bleeding group are higher than the control group and the differences have statistic significance(P<0. 05);plasma protein,platelet count and cholesterin are lower than the bleeding group and the differences have statistic significance( P<0. 05). Logisitc regression analysis(OR=0. 67)and platelet count(OR=0. 74)are protection factors of esophageal and gastric var-ices bleeding in patients with cirrhosis,inner diameter of portal vein(OR=4. 68),spleen thickness(OR=3. 92),red-color sign (OR=2. 26)and grading of esophageal varices(OR=3. 71)are risk factors of esophageal and gastric varices bleeding in patients with cirrhosis. Conclusion Inner diameter of portal vein,spleen thickness,plasma protein,platelet count,red-color sign and grad-ing of esophageal varices are correlative factors of esophageal and gastric varices bleeding in patients with cirrhosis which can point out bleeding risks.

关键词

肝硬化/食管胃静脉曲张破裂出血/风险/预测

Key words

cirrhosis/esophageal gastric varices bleeding/risk/prediction

分类

临床医学

引用本文复制引用

黄鹤,伦伟健,梁晓燕,刘浏,贾柳萍..肝硬化食管胃静脉曲张破裂出血相关危险因素分析[J].四川医学,2016,37(3):320-323,4.

四川医学

OACSTPCD

1004-0501

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