中国伤残医学2016，Vol.24Issue(7)：4-5,2.DOI:10.13214/j.cnki.cjotadm.2016.07.003
AQP8在老年宫颈鳞癌患者中的表达及意义
Expression of AQP8 Protein in Cervical Squamous Carcinoma and its Clinical Significance
陈志铭 1张宇峰 1侯晓旭2
作者信息
- 1. 鹤壁市第一人民医院，河南鹤壁 458000
- 2. 郑州大学第一附属医院
- 折叠
摘要
Abstract
Objective:To investigate the expression of AQP 8 protien in cervical squamous carcinoma and explore the relationship be-tween AQP8 protien expression and the development of the cervical squamous carcinoma .Methods:The expression of AQP8 protein in 50 cases of cervical squamous carcinoma ,40 cases of cervical intraepithelial neoplasia ( CIN) and 20 cases of normal cervices were examined by immunohistochemical technology .Results:The positive expression in parenchymal cells increasesd accompany with squamous epitheli -um malignant transformation,there were significant differences (P<0.05);no correlation was found between AQP8 protein expression and age ,tumor size or clinical stage (P>0.05).Exprission of AQP8 in cases with lymph node metastasis was higher than without lymph node metastasis (P<0.05).Conclusion:High expression of AQP8 may play a key role in the happen , development and lymph -node metas-tasis of cervical squamous carcinoma .关键词
水通道蛋白8/宫颈鳞癌/宫颈上皮内瘤变/免疫组织化学Key words
AQP8/Cervical squamous carcinoma/Cervical intraepithelial neoplasia/Immunohistochemical分类
医药卫生引用本文复制引用
陈志铭,张宇峰,侯晓旭..AQP8在老年宫颈鳞癌患者中的表达及意义[J].中国伤残医学,2016,24(7):4-5,2.
