山东中医药大学学报2016，Vol.40Issue(2)：140-142,3.
天麻钩藤饮治疗风阳上扰型急性脑梗死氧化应激机制临床研究
Clinical Study on Oxidative Stress Mechanism of Acute Cerebral Infarction of Wind Yang Hyperactivity Treated by Tianma Gouteng Decoction
摘要
Abstract
Objective:To study the oxidative stress mechanism of acute cerebral infarction of wind Yang hy-peractivity type treaded by Tianma Gouteng decoction. Methods:Total 100 patients with acute cerebral infarc-tion of wind Yang hyperactivity type were randomly divided into the treatment group(56 patients) and control group(44 patients). The conventional treatment was given to the two groups while Tianma Gouteng decoction was only given to the treatment group for two courses,7 days in each course. The serum levels of malondi-aldehyde (MDA),oxidized low density lipoprotein (ox-LDL),superoxide dismutase (SOD),glutathione peroxi-dase(GSH-PX) and the changes of nerve function defect score were observed before and after treatment. Results:The levels of MDA and ox-LDL decreased,the levels of SOD and GSH-PX elevated. Oxidative stress indicators of the treatment group were improved compared with those of the control group(P<0.05). Conclu-sion:Tianma Gouteng decoction had good curative effect in treating acute cerebral infarction of wind Yang hyperactivity type. The mechanism may be realized through the way of oxidative stress of acute cerebral in-farction.关键词
天麻钩藤饮/风阳上扰/脑梗死/氧化应激Key words
Tianma Gouteng decoction/wind Yang hyperactivity/cerebral infarction/oxidative stress分类
医药卫生引用本文复制引用
王艳旭,李世举,梁晖,陈甦,阮甦,严年文..天麻钩藤饮治疗风阳上扰型急性脑梗死氧化应激机制临床研究[J].山东中医药大学学报,2016,40(2):140-142,3.基金项目
福建省卫生厅青年科研课题(编号:2011-2-34) （编号:2011-2-34）
