山东医药2016,Vol.56Issue(11):41-43,3.DOI:10.3969/j.issn.1002-266X.2016.11.015
老年非ST段抬高型急性心肌梗死患者临床特征及预后影响因素
Clinical characteristics and prognostic factors of elderly patients with non-ST-segment elevation acute myocardial infarction
摘要
Abstract
Objective To investigate the clinical characteristics and prognostic factors of elderly patients with non-ST-seg-ment elevation acute myocardial infarction (NSTEMI).Methods Totally 135 elderly patients with acute myocardial infarction, including 72 patients with NSTEMI and 63 patients with ST segment elevation acute myocardial infarction (STEMI) were select-ed.The clinical data between patients with NSTEMI and with STEMI were compared .Cox regression model was used to analyze the prognostic factors for elderly patients with NSTEMI .Results The NSTEMI elderly patients had more cases of patients with diabetes mellitus (30 vs.12), hypertension (49 vs.31) and heart failure (45 vs.27) than STEMI elderly patients and had less cases of persistent chest pain (40 vs.53), lower levels of peak creatine kinase〔(829.55 ±125.64) IU/L vs.(2354.45 ± 351.01) IU/L〕and troponin I peak〔(0.86 ±0.24) ng/mL vs.(1.86 ±0.64) ng/mL〕 (all P<0.05).The rates of recurrent angina, heart failure and mortality in NSTEMI elderly patients were higher than STEMI patients during 1 year after discharge (24.3%vs.11.7%, 18.6%vs.6.7%, 25.7%vs.8.3%) (all P<0.05).Old age (>65 years) (HR=2.13), heart failure (HR=3.37) and Killip≥3 level at admission (HR=1.79) were risk prognostic factors for NSTEMI elderly patients and aspirin (HR=0.51) was the protective prognostic factor.Conclusions There are more diabetes, hypertension, heart failure and less persistent chest pain and lower peak creatine kinase and troponin I peak in NSTEMI elderly patients than those in the STEMI eld-erly patients.The long-term prognosis of elderly patients with NSTEMI is poor .The NSTEMI patients with old age (>65 years), heart failure or multiple Killip≥3 level at admission are more likely to undergo poor prognosis and patients with aspirin may de-crease the poor prognosis.关键词
心肌梗死/非ST段抬高型急性心肌梗死/老年人/心力衰竭Key words
myocardial infarction/non-ST-segment elevation acute myocardial infarction/aged/heart failure分类
临床医学引用本文复制引用
刘辉,张燕,张少利,张永春,岳兵..老年非ST段抬高型急性心肌梗死患者临床特征及预后影响因素[J].山东医药,2016,56(11):41-43,3.基金项目
河南省科技发展计划项目(142300410191). (142300410191)