西北国防医学杂志2016，Vol.37Issue(3)：164-166,3.DOI:10.16021/j.cnki.1007-8622.2016.03.009
毛细管气相色谱法同时测定复方樟脑搽剂中樟脑、薄荷脑含量
Content determination of camphor and menthol in compound camphor liniment by capillary gas chromatography
王俊丽 1李加恒 1盖静1
作者信息
- 1. 兰州军区联勤部药品仪器检验所,甘肃兰州 730050
- 折叠
摘要
Abstract
Objective:To establish a method for the determination of camphor and menthol in compound camphor liniment by capillary gas chromatography (GC).Methods:The content was determined by GC combined with Agilent 19095N-123 INNOWAX capillary chromatographic column (30 m × 0.53 mm,1 μm).Column temperature:120℃,injector temperature:220℃,FID detector temperature:260℃.Injector volume was 1 μl,split ratio was 20 ∶ 1.Nitrogen was used as carrier gas,the flow of column was 6.0 ml/min,air:450 ml/min,hydrogen:40 ml/min.Results:The linear range were 0.2016-2.0160 mg/ml (r=0.9999),0.3920-3.9200 mg/ml (r =0.9999) for camphor and menthol respectively.The corresponding average recovery rate were 99.01％ (RSD=1.3％) and 97.80％ (RSD=1.8％).Conclusion:This method is simple,accurate and with good reproducibility,which can be used as quality control for compound camphor liniment.关键词
气相色谱法/复方樟脑搽剂/樟脑/薄荷脑/含量测定Key words
gas chromatography/compound camphor liniment/camphor/menthol/content determination分类
药学引用本文复制引用
王俊丽,李加恒,盖静..毛细管气相色谱法同时测定复方樟脑搽剂中樟脑、薄荷脑含量[J].西北国防医学杂志,2016,37(3):164-166,3.
