厦门大学学报（自然科学版）2016，Vol.55Issue(2)：162-167,6.DOI:10.6043/j.issn.0438-0479.2016.02.003
PLGA及PLGA-PEG-PLGA水凝胶的制备
Preparation of PLGA and PLGA-PEG-PLGA Hydrogels
刘迪 1黄晓英 2何旭敏 1林旭 2夏海平1
作者信息
- 1. 厦门大学化学化工学院,福建 厦门 361005
- 2. 厦门普瑞安生物科技有限公司,福建 厦门 361000
- 折叠
摘要
Abstract
In this study,an optimized process of poly (lactic-co-glycolic acid)(PLGA)preparation was reported,including shorting synthetic time to obtain PLGA with expected molecular weight,by controlling the reaction conditions of operation.An optimized process of its post-treatment was also investigated,reducing the residue-level of toxic organic solvent.Furthermore,this study was focused on co-polymerization of PLGA(?Mn≥2000)and polyethylene glycol (PEG)to form PLGA-PEG-PLGA triblock copolymers. The solution-gel conversion properties were characterized by their phase diagrams of the corresponding PLGA-PEG-PLGA aqueous solution.关键词
聚乳酸乙醇酸(PLGA)/聚乙二醇(PEG)/优化/PLGA-PEG-PLGA/三嵌段共聚物/水凝胶Key words
PLGA/PEG/optimization/PLGA-PEG-PLGA/triblock copolymers/hydrogel分类
化学化工引用本文复制引用
刘迪,黄晓英,何旭敏,林旭,夏海平..PLGA及PLGA-PEG-PLGA水凝胶的制备[J].厦门大学学报（自然科学版）,2016,55(2):162-167,6.
