临床医学工程2016，Vol.23Issue(3)：353-354,2.DOI:10.3969/j.issn.1674-4659.2016.03.0353
脓毒血症患者抗凝治疗对凝血和炎性指标的影响研究
Impact of Anticoagulant Therapy on the Blood Coagulation and Inflammatory Markers of Patients with Sepsis
朱建军1
作者信息
- 1. 广东省信宜市人民医院ICU，广东茂名525300
- 折叠
摘要
Abstract
Objective To explore the impact of low molecular weight heparin for anticoagulant therapy on the blood coagulation and inflammatory markers of patients with sepsis. Methods A total of 84 cases of sepsis patients admitted to our hospital from March 2013 to October 2014 were selected and randomly divided into two groups equally. The control group received routine therapy, while the intervention group received low molecular weight heparin on the basis of routine therapy. The serum high sensitivity C-reactive protein (hs-CRP), procalcitonin (PCT) and D-Dimer, and the incidence of MODS were compared between two groups. Results After therapy, the inflammatory markers of intervention group were significantly lower than those of control group (P <0.05). The incidence rate of MODS of intervention group was significantly lower than that of control group (P<0.05). Conclusions After anticoagulant therapy with low molecular weight heparin, the expressions of inflammatory markers including hs-CRP, PCT and D-Dimer, and the incidence of MODS of sepsis patients decrease significantly. Early anticoagulant therapy should be taken for sepsis patients to reduce the incidence of inflammatory response.关键词
脓毒血症/低分子肝素治疗/凝血功能/炎性指标Key words
Sepsis/Low molecular weight heparin/Coagulation function/Inflammatory markers分类
临床医学引用本文复制引用
朱建军..脓毒血症患者抗凝治疗对凝血和炎性指标的影响研究[J].临床医学工程,2016,23(3):353-354,2.
