中国医学前沿杂志（电子版）2016，Vol.8Issue(2)：53-56,4.
布地奈德联合扎鲁司特治疗支气管哮喘的临床效果及对患者肺功能和炎性因子的影响
Effect of budesonide combined with zafirlukast on pulmonary function and inflammatory factor of the patients with bronchial asthma
薛世民 1贾娟1
作者信息
- 1. 榆林市第二医院 呼吸内科，陕西 榆林 719000
- 折叠
摘要
Abstract
Objective To explore the effect of budesonide combined with zafirlukast on pulmonary function and inflammatory factor of the patients with bronchial asthma. Method According to the time of admission and random number table method, 106 patients with bronchial asthma in our hospital were divided into budesonide + zafirlukast group (budesonide combined with zafirlukast therapy) and budesonide group (budesonide treatment alone), two groups of patients were treated with routine treatment of asthma, 7 days for a course of treatment, a total of 2 courses of treatment. Result FEV1, FEV1/FVC and PEF of budesonide +zafirlukast group were higher than budesonide group (P < 0.01). The levels of IL-4、IL-8 and TNF-α of budesonide + zafirlukast group were lower than budesonide group (P < 0.01). The total effective rate of budesonide + zafirlukast group was higher than budesonide group (P < 0.01). Conclusion Budesonide combined with zafirlukast can improve pulmonary ventilation function of patients with bronchial asthma and reduce the levels of inflammatory factors, and improve asthma symptoms.关键词
支气管哮喘/布地奈德/扎鲁司特Key words
Bronchial asthma/Budesonide/Zafirlukast引用本文复制引用
薛世民,贾娟..布地奈德联合扎鲁司特治疗支气管哮喘的临床效果及对患者肺功能和炎性因子的影响[J].中国医学前沿杂志（电子版）,2016,8(2):53-56,4.
