中国药业2016，Vol.25Issue(4)：73-74,75,3.
足光散质量标准提高研究
Improvement of Quality Standard of Zuguang Powder
肖琦 1阳文武 1朱泽兵 1杨潇潇 1李柏群2
作者信息
- 1. 重庆市万州食品药品检验所，重庆 404000
- 2. 重庆市三峡中心医院，重庆 404000
- 折叠
摘要
Abstract
Objective To improve the quality standard of Zuguang Powder. Methods Salicylic acid and benzoic acid were identified by HPLC. The Diamonsil C18 column(250 mm × 4. 6 mm,5 μm)was used with the mobile phase of methanol-0. 1% phosphoric acid(45 :55) at a flow rate of 1. 0 mL/min,the detection wavelength was set at 226 nm. Results The peak retention time of the test solution cor-responds to the reference solution with the negative control without the corresponding peaks. Benzoic acid was linear within 60. 30-1 206. 04 μg/mL( r=0. 999 8),salicylic acid was linear within 40. 54-810. 81 μg/mL( r=0. 999 7);the average recovery rate of benzoic acid was 99. 47%,RSD=0. 76%( n=6),the average recovery rate of salicylic acid was 95. 93%,RSD=1. 15%( n=6). Conclusion The method is accurate and repeatable,which can be used for the quality control of Zuguang Powder.关键词
足光散/苯甲酸/水杨酸/高效液相色谱法/质量标准Key words
Zuguang Powder/benzoic acid/salicylic acid/HPLC/quality standard分类
中医学引用本文复制引用
肖琦,阳文武,朱泽兵,杨潇潇,李柏群..足光散质量标准提高研究[J].中国药业,2016,25(4):73-74,75,3.
