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注射用乌司他丁联合参麦注射液治疗急性胰腺炎57例临床研究

辜新奇 施建平 金怒云

中国药业2016,Vol.25Issue(5):30-32,3.
中国药业2016,Vol.25Issue(5):30-32,3.

注射用乌司他丁联合参麦注射液治疗急性胰腺炎57例临床研究

Ulinastatin Combined with Shenmai Injection for Treating Acute Pancreatitis in 57 Cases

辜新奇 1施建平 1金怒云1

作者信息

  • 1. 上海市浦东医院消化内科,上海 201399
  • 折叠

摘要

Abstract

Objective To explore the efficacy of ulinastatin combined with Shenmai Injection in treating acute pancreatitis, and to observe the improvement of urine amylase, blood routine and biochemical indexes. Methods 150 patients from June 2014 to June 2015 were selected and divided into the control group and the treatment group according to the sequence of patient records and the wishes of the patients, 75 cases in each group. The control group received ulinastatin treatment (20 U/d, once daily for 5 d;10 U/d, once daily for 5 d), the treatment group received ulinastatin combined with Shenmai Injection treatment ( 50 mL/d, once daily for 10 d ) . After continuous medication for 10 d, the improvement of urine amylase, blood and biochemical indexes case were detected, analyzed and compared. Results Before treatment, the urine amylase, blood biochemical indexes of the two groups showed no statistically significant difference ( P ﹥ 0. 05 ); after treatment, the indexes in both groups significantly decreased ( P ﹤ 0. 05 ) , and the treatment group was significantly lower than the control group ( P ﹤ 0. 05 ) . The total effective rate in the control group was 85. 33%, which was significantly lower than 93. 33% of the treatment group ( P ﹤ 0. 05 ) . The incidence rate of adverse reaction in the treatment group was 9. 33%, which had no statistically significant difference with 8. 00% in the control group ( P ﹥ 0. 05 ) . Conclusion Ulinastatin combined with Shenmai Injec-tion in treating acute pancreatitiscan significantly reduce the patient ’ s urine amylase, blood and biochemical indexes, has better clinical efficacy, which is worthy of clinical promotion.

关键词

乌司他丁/参麦注射液/急性胰腺炎/血尿淀粉酶/血常规/血生化

Key words

ulinastatin/Shenmai Injection/acute pancreatitis/amylase/blood routine/blood biochemical indicators

分类

医药卫生

引用本文复制引用

辜新奇,施建平,金怒云..注射用乌司他丁联合参麦注射液治疗急性胰腺炎57例临床研究[J].中国药业,2016,25(5):30-32,3.

中国药业

OACSTPCD

1006-4931

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