中国药业2016，Vol.25Issue(5)：82-83,2.
奥沙利铂联合卡培他滨治疗进展期胃癌40例临床评价
Efficacy and Safety Evaluation of Oxaliplatin Combined with Capecitabine for Treating Advanced Gastric Cancer in 40 Cases
苏克1
作者信息
- 1. 广西壮族自治区南宁市红十字会医院，广西 南宁 530012
- 折叠
摘要
Abstract
Objective To study the clinical efficacy and safety of oxaliplatin combined with capecitabine for patients with advanced gas-tric cancer. Methods 80 patients with advanced gastric cancer were randomized into the control group ( ECF chemotherapy ) and the observation group ( the treatment of oxaliplatin combined with capecitabine ) according to the random number method, 40 cases in each group. The clinical efficacy, toxicity, and the life quality on pre- and post-treatment in the two groups were compared. Results Com-pared with the control group , the total effective rate was significantly increased in the observation group ( 85. 00% vs 57. 50%, P ﹤ 0. 05 );the toxicity incidence of gastrointestinal reactions and bone marrow suppression were obviously reduced in the observation group ( P ﹤ 0. 05 );the each dimension and total scores of life quality on post-treatment were significantly increased in the obser-vation group ( P ﹤ 0. 05 ) . Conclusion The treatment of oxaliplatin combined with capecitabine for advanced gastric cancer has the significant efficacy and less toxicity, and obviously improve the patients' life quality.关键词
奥沙利铂/卡培他滨/进展期胃癌/生活质量Key words
oxaliplatin/capecitabine/advanced gastric cancer/life quality分类
药学引用本文复制引用
苏克..奥沙利铂联合卡培他滨治疗进展期胃癌40例临床评价[J].中国药业,2016,25(5):82-83,2.
