军事医学2016，Vol.40Issue(3)：234-236,3.DOI:10.7644/j.issn.1674-9960.2016.03.017
GM、G试验及真菌培养鉴定对肺部侵袭性真菌感染的诊断价值
Values of G test and GM test combined with fungal culture method for diagnosis of invasive fungal infection in lungs
摘要
Abstract
Objective To evaluate the diagnostic efficiency of deep fungal infection by detecting the serum galactomannan ( GM) and bronchoalveolar lavage fluid ( BALF) GM, serum G test and fungal culture of BALF in patients with suspected invasive fungal infection ( IFI) in lungs.Methods A retrospective analysis was performed of the results of serum /BALF GM test ,serum G test and BALF culture from 148 patients with suspected pulmonary IFI .The indexes involved sensitivity , specificity , positive predictive value , negative predictive value , as well as diagnostic capacity for deep fungal infection with separated or combined tests .Results Among the 148 cases, 48 cases were clinically diagnosed with IFI and the rest were excluded.Among the 48 IFI cases, 3 cases were positive in serum GM test , 25 cases were positive in BALF GM test , 31 cases were positive in G test and 30 cases were positive in fungal culture .The combined detection showed a sensitivity of 91.6%,specificity of 70.0%, positive predictive value of 59.5% and negative predictive value of 94.6%.Conclusion The combination of GM/G tests and fungal culture can significantly improve the clinical diagnostic efficiency of pulmonary IFI .关键词
肺真菌感染/肺泡灌洗液/诊断/检测/半乳甘露聚糖/(1,3)-β-D葡聚糖试验/真菌鉴定Key words
invasive fungal infection/bronchoalveolar lavage fluid/diagnosis/detection/galactomannan/(1,3)-β-D-glucan test/fungal identification分类
医药卫生引用本文复制引用
马清,于农,尹秀云,金欣,陈水平,陈建魁..GM、G试验及真菌培养鉴定对肺部侵袭性真菌感染的诊断价值[J].军事医学,2016,40(3):234-236,3.基金项目
国家科技重大专项资助项目（2013ZX10004203）；国家重大科学仪器设备开发专项 （）
