检验医学与临床2016，Vol.13Issue(7)：898-901,4.DOI:10.3969/j.issn.1672-9455.2016.07.014
血清和 EPS 中雌雄激素水平对Ⅲ型前列腺炎患者勃起功能的影响
Influences of sex hormone level in serum and expressed prostatic secretion on erectile function in patients with type Ⅲ prostatitis
摘要
Abstract
Objective To explore the correlation between the change of estradiol and testosterone (E2 ,T ) in serum and expressed prostatic secretion (EPS) with the erectile function in the patients with type Ⅲ prostatitis(CP/CPPS) .Methods 372 patients with type Ⅲ prostatitis in our hospital from September 2013 to September 2014 were chosen and divided into the research groupⅠ(WBC≥10/HP ,213 cases) and Ⅱ(WBC<10/HP ,159 cases) according to the test results of EPS ,and then these 372 cases of type Ⅲ prostatitis were divided into the group A(≤21 points) and B (>21 points) according to the international index of erectile function‐5(IIEF‐5) scores .Other contemporane‐ous186 individuals undergoing the healthy physical examination were chosen as the control group .The levels of E2 and T in serum and EPS were detected by ELISA .NIH‐CPSI index and IIEF‐5 index were applied to evaluate the pa‐tients .The correlation between the E2 ,T levels in serum and EPS with the erectile function was analyzed .Results The E2 levels in serum and E2/T in serum and EPS of the research groupⅠ and Ⅱ were significantly higher than those in the control group ,but the T level was lower than that in the control group ,the differences were statistically significant(P<0 .05);99 cases in the research group Ⅰwere included in the group A ,which were more than 87 cases in the research groupⅡ ,but the difference was not statistically significant(χ2 =0 .824 ,P=0 .364) ;the serum T level in the group A was significantly lower than that in the group B and the control group ,but the E2/T ratio in EPS was significantly higher than that in the group B and the control group ,moreover ,the E2 level in EPS was significantly in‐creased compared with the group B ,the difference was statistically significant (P<0 .01);the IIEF‐5 scores had the positive correlation with the T level in serum and EPS(r=0 .137 ,0 .145 ,P=0 .031 ,0 .022) ,and had the negative cor‐relation with the E2 level in EPS and the E2/T ratio in serum and EPS (r= -0 .132 ,-0 .167 ,-0 .152 ,P=0 .038 ,0 .008 ,0 .017) ,and had no correlation with NIH‐CPSI scores (r=0 .025 ,P=0 .695) .Conclusion The change of E2 and T levels in serum and EPS could influence the erectile function in the patients with type Ⅲ prostatitis (CP/CPPS) .关键词
血清/EPS/雌雄激素/Ⅲ型前列腺炎/勃起功能Key words
serum/EPS/sex hormone level/type Ⅲ prostatitis/erectile function引用本文复制引用
吴炜嘉,夏昕晖,李梅,黄彩辉,姜海洋,郑汉雄..血清和 EPS 中雌雄激素水平对Ⅲ型前列腺炎患者勃起功能的影响[J].检验医学与临床,2016,13(7):898-901,4.基金项目
广东省深圳市福田区卫生公益性科研资助项目（FTWS2014009）。 （）
