临床神经外科杂志2016，Vol.13Issue(2)：114-117,4.DOI:10.3969/j.issn.1672-7770.2016.02.010
质子磁共振波谱分析创伤性蛛网膜下腔出血腰大池持续引流患者脑代谢的变化
Analysis of cerebral metabolic changes by hydrogen proton magnetic resonance spectroscopy in patients with lumbar continuous drainage of cerebrospinal fluid on traumatic subarachnoid hemorrhage
摘要
Abstract
Objective To explore by hydrogen proton magnetic resonance spectroscopy ( 1 H-MRS) in patients with lumbar continuous drainage of cerebrospinal fluid on traumatic subarachnoid hemorrhage( tSAH) to analysis of cerebral metabolic changes.To evaluate the clinical efficacy and prognosis of patients with subarachnoid hemorrhage caused by trauma.Methods 80 patients who underwent traumatic subarachnoid hemorrhage of lumbar continuous drainage of cerebrospinal fluid from October 2012 to October 2015 were divided into the observation group and the control group (40 patients each) randomly.The observation group in addition to using the conventional method, be admitted to hospital the third heaven treated by continuous drainage of lumbar cistern.Patients of control group were only given routine treatment.After admission, two groups were 3, 8 ,14 days to examination cerebral blood flow changes by Transcranial doppler and compared the clinical efficacy each other.Two groups of patients on day 14 of proton magnetic resonance spectroscopy analysis of the frontal lobe, basal ganglia, pillow leaf NAA, Cho, Cr and NAA /Cr, Cho /Cr value changes, the indexes were statistically analyzed.Results The observation group of patients with cerebral blood flow velocity, clinical efficacy and the main symptoms of the disappearance rate was significantly better than the control group, P <0.05.The frontal lobe, basal ganglia area and occipital lobe NAA/Cr in the observation group were significantly higher than those in the controlgroup,and the /Cr Cho values were lower than those in the control group,P<0.05.Conclusion Continuous drainage of lumbar can relieve cerebral vasospasm in patients with traumatic subarachnoid hemorrhage, improve the clinical symptoms,1 H-MRS has important reference value for evaluating clinical curative effect and prognosis.关键词
质子磁共振波谱/脑代谢/创伤性蛛网膜下腔出血/腰大池持续引流Key words
hydrogen proton magnetic resonance spectroscopy/cerebral infarction/traumatic subarachnoid hemorrhage/lumbar continuous drainage of fluid cerebral vasospasm分类
医药卫生引用本文复制引用
吴海滨,赵冬青,王科..质子磁共振波谱分析创伤性蛛网膜下腔出血腰大池持续引流患者脑代谢的变化[J].临床神经外科杂志,2016,13(2):114-117,4.基金项目
杭州市科技局项目(2013ZJXSYY02) （2013ZJXSYY02）
