临床神经外科杂志2016，Vol.13Issue(2)：131-135,5.DOI:10.3969/j.issn.1672-7770.2016.02.014
室管膜下瘤9例临床分析
Clinical analysis of 9 paitients with subependymoma
宋坤 1王娟 1柴学 2刘文 2张巧全 1周金宝 1张玉梅 1朱海青1
作者信息
- 1. 210029 南京医科大学附属脑科医院病理科
- 2. 210029 南京医科大学附属脑科医院放射科
- 折叠
摘要
Abstract
Objective To study clinical, imaging and pathologic features of subependymoma. Methods The clinical data of 9 patients with subependymoma were analyzed retrospectively.Surgical removal of the tumor tissue specimens were performed using pathologic and immunohisto-chemical examination.Results Male and female of this group was with a ratio of 2:1 with mean age 54 years. Postoperative follow-up of 10-109 months, there were no metastasis and recurrence.MRI demon-strated the tumors located in the lateral ventricle of 8 cases and the right temporal lobe in 1 case. There were 6 cases showed iso-signal,1 case showed low-signal and 1 case showed high-signal on T1 WI.There were 6 cases showed high-signal and 2 cases showed iso-signal on T2 WI.Enhancement scan demonstrated 4 cases got slight enhancement and 4 cases were without enhancement respectively.Pathologic examination showed that the tumors were highly fibrillar and clusters of nuclei embedded in it.Most cases showed microcystic formation except 1 case in the right temporal lobe.Immunohistochemical examination was positive for GFAP,S-100 and Vimentin and negative for SYN,EMA and Neu-N.Ki-67 labelling indices showed 1 case was 4%and 8 cases were 1%-3%. Conclusions Subependy-moma occurs most freqently in old male.It carries a slowly progress and good prognosis.It occurs mostly in the lateral intraventricular, whereas rarely in the brain parenchyma.Correct understanding the clinical, imaging and pathological are beneficial to the diagnosis and treatment.关键词
室管膜下瘤/临床特点/影像学/病理Key words
subependymoma/clinical features/imaging/pathology分类
医药卫生引用本文复制引用
宋坤,王娟,柴学,刘文,张巧全,周金宝,张玉梅,朱海青..室管膜下瘤9例临床分析[J].临床神经外科杂志,2016,13(2):131-135,5.
