生殖医学杂志2016，Vol.25Issue(4)：325-330,6.DOI:10.3969/j.issn.1004-3845.2016.04.007
辅助生殖技术出生的学龄期儿童行为发育的随访研究
A follow-up study of behavior in children of school age conceived by assisted reproductive technology
摘要
Abstract
Objective: To observe whether there is a difference in behavior between the children of school-age conceived by the assisted reproduction technology ( ART) and children naturally conceived ( NC). <br> Methods: The ART group consisted by 125 ART children aged 6 to 11 years, who were born from March 2001 to March 2009 , and the NC group included 203 children naturally conceived at the same age range. A questionnaire was used to record the child’ s basic information. And the Achenbach Child Behavior scale was used for each child’ s social ability and behavior assessment. <br> Results: In male group,there were no significant differences in the scores of social ability and proportion of abnormal score of behavior ability between ART children ( ART group ) and naturally conceived children ( NC group) (P>0. 05). The girls from ART group had a significantly lower score in activity ability than that of naturally conceived girls (4. 74±2. 16 vs. 5. 52±2. 20,P<0. 05),but the proportion of abnormal score of behavior ability had no significant difference ( P>0. 05 ) . The results of multiple linear regression for girl ' s activity showed that the children age and the mother’ education level had influence on the social ability (P>0. 05),but whether ART baby or twins,height,weight,etc. did not affect child’s ability of activity (P>0. 05). <br> Conclusions: The girls conceived by ART at school-age have lower score of social ability than naturally conceived girls. There were no significant differences in the other behavioral development index,no matter boys or girls,between the children conceived by ART and the naturally conceived children.关键词
辅助生殖技术/试管婴儿/学龄期儿童/行为发育Key words
Assisted reproductive technologies/Test-tube baby/Children of school age/Behavior development引用本文复制引用
文娅,梁怡婳,焦雪丹,林海燕,陈晓丽,杨冬梓,张清学..辅助生殖技术出生的学龄期儿童行为发育的随访研究[J].生殖医学杂志,2016,25(4):325-330,6.基金项目
广东省自然科学基金(2015A03031305) （2015A03031305）
