摘要
Abstract
Objective To investigate the clinical significance of CT pulmonary artery embolization index ( PAOI) in elderly patients with acute pulmonary embolism ( APE) .Methods From 2010 January to 2015 June, 120 patients with APE who received CT pulmonary angiography ( CTPA) examination at Hainan Nongken hospital were enrolled.Based on Mastora scoring method for PAOI score, according to PAOI, they was divided into mild group ( PAOI<30%) with 45 cases, moderate group (30%~50%PAOI) with 50 cases, severe group (PAOI>50%) with 25 cases.To analyze the value of PAOI in eval-uating the prognosis of APE patients, and to evaluate the cardiac function and blood gas index.Results The level of, PaCO2 and SaO2 decreased gradually with the severity of the disease, and there were significant differences of PaO2 between the 3 groups ( P <0.05).With the increase of the severity of the disease, RVd, RVd/LVd, RVs, RVs/LVs levels gradually in-creased, and there were statistically significant differences of RVd and RVs between the 3 groups ( P <0.05) .At the same time, the proportion of IVSD, IVCR and AZR appeared gradually increasing, among which there were significant differences of IVSD and AZR between the 3 groups ( P <0.05).Correlation analysis showed that PAOI and PaO2 was negative correlated (r =-0.408, P =0.022), and exist positive correlation with RVD ( r =0.445, P =0.010), RVd/LVd ( r =0.669, P =0.007), RVs ( r =0.429, P =0.012), RVs/LVs ( r =0.387, P =0.031), IVSD ( r =0.558, P =0.005) and IVCR ( r =0.583, P =0.006), and showed negative correlation with LVD ( r =-0.551, P =0.009).PAOS has certain predictive and diagnosis value (AUC=0.834, 95%CI 0.511-0.926, P =0.002), the optimal cutoff value was 58.9%, sensitivity was 85.3%, the specificity was 89.9%.Conclusion Mastora scoring system based on the PAOI score can effec-tively estimate the severity of the disease in patients with APE, and predict the risk of death.关键词
CT肺动脉栓塞指数/急性肺栓塞/老年人/诊断意义Key words
Pulmonary artery embolization index/Acute pulmonary embolism/The elderly/Clinical value
