胡露露 1林兆全 1张晋 2刘慧 1龚忠诚 1凌彬 1克热木·阿巴斯 1尹小朋 1邵博 1王冰1
作者信息
- 1. 新疆医科大学第一附属医院颌面肿瘤外科 新疆 乌鲁木齐 830054
- 2. 新疆医科大学第五附属医院口腔颌面外科 新疆 乌鲁木齐 830000
- 折叠
摘要
Abstract
ObjectiveTo detect the level of EBV in patients with oral and maxillofacial lymphoma and analyze the correlation between level of EBV and the clinicopathological characteristics.Methods Select patients with oral and maxillofacial lymphoma at the First Affiliated Hospital of Xinjiang Medical University from January 1,2014 to January 1,2015,ISH was used to detect the level of EBV in these patients. The correlation was analyzed from sex, age, tumor location, HL lymph nodes, clinical stage, tumor type,pathological type and LDH level.ResultsThe positive expression of ISH was 45% in EBV infection. And sex, age, tumor location, the number of lesions was not related with the result (P>0.05). While the result was related with some aspects of the occuring cite of the internal and external of HL lymph nodes (node within 60%, 25%,P=0.012) and clinical staging (I+II:30.8%, III+IV:71.4%,P=0.023), tumor type (NHL:54.9%, HL:11.1%,P=0.017), pathological type (NKT:84.6%, BCL:23.1%, TCL:20%, HL:11.2%,P=0.034), LDH (lactate dehydrogenase (LDH) > 250mmol/l:60%, LDH is less than or equal to 250mmol/l:36%,P = 0.026) (P<0.05); HL lymph node and tumor staging, clinical stage, pathological type, LDH level were independent risk factors of EBV infection in patients with maxillofacial lymphoma (P<0.05).Conclusion EBV infection in oral and maxillofacial lymphoma patients was highly positive expression, HL lymph nodes and the clinical stage, clinical stage,tumor classiifcation, pathological type, LDH level are the independent risk factors of EBV infection in patients with maxillofacial lymphoma.关键词
口腔颌面部肿瘤/恶性淋巴瘤/EB病毒/临床病理特征/相关性分析Key words
oral and maxillofacial tumor/lymphoma/EP stein-Barr virus/clinical and pathological features/correlation analysis分类
医药卫生
