中国美容医学2016，Vol.25Issue(2)：37-39,3.
鼻息肉术后囊泡组织中微血管密度及血管内皮生长因子在上皮化进程中的表达及意义
Expression and signiifcance of MVD and VEGF on vesicles in the process of epithelialization after endoscopic polypectomy
王军旗 1张超 1马明瑛1
作者信息
- 1. 河南科技大学第一附属医院耳鼻咽喉-头颈外科 河南 洛阳 471000
- 折叠
摘要
Abstract
Objective To investigate the expression and signiifcance of Microvessel Density(MVD) and Vascular Endothelial Growth Factor(VEGF) in the vesicles tissue after endoscopic polypectomy.Methods Forty patients(80 sides) with chronic nasal polyps were included.The vesicles tissue removed from nasal cavity after the operation was collected as experimental group, while the control group encompassed nasal polyps and inferior turbinate tissue.Then compare MVD and the expression levels of average optical density in the positive area in both two groups and analyse their relations in vesicles tissue.Results MVD in the nasal polyps,the vesicle tissue and inferior turbinate tissues were gradually increased,among of which the difference was statistically signiifcant (P<0.05). The average optical density of VEGF in the positive area in nasal polyps,the vesicle organization and inferior turbinate decreased in turn, where the difference was also statistically signiifcant (P<0.05). There was negative correlation between the average optical density of MVD and VEGF in positive regions.Conclusion The dynamic changes of the MVD and VEGF can be used as indicators to monitor the outcome of mucosa prognosis after endoscopic sinus surgery.关键词
鼻息肉/MVD/VEGF/免疫组化/功能性鼻内镜手术Key words
nasal polyps/Microvessel Density(MVD)/Vascular Endothelial Growth Factor(VEGF)/immunohistochemistry/functional endoscopic sinus surgery分类
医药卫生引用本文复制引用
王军旗,张超,马明瑛..鼻息肉术后囊泡组织中微血管密度及血管内皮生长因子在上皮化进程中的表达及意义[J].中国美容医学,2016,25(2):37-39,3.
