中国美容医学2016,Vol.25Issue(2):55-57,3.
ALA-PDT联合0.1%他克莫司软膏治疗玫瑰痤疮疗效观察与分析
Observation of therapeutic effect of 5-aminolevulinic acid-photodynamic therapy combined with tacrolimus 0.1% ointment in the treatment of rosacea
杨宪鲁 1王海燕 2雷旭光 1苏芳 1董岩 1孙玉鲁1
作者信息
- 1. 山东省威海市立医院皮肤科 山东 威海 264200
- 2. 山东省威海市妇幼保健院病理科 山东 威海 264200
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of combination therapy of 5-aminolevulinic Acid-photodynamic therapy (ALA-PDT) and tacrolimus 0.1% ointment in the treatment of rosacea.Methods Ninety-five cases with rosacea were randomly divided into three groups. Treatment and control group 1 adopted the treatment of ALA-PDT once every week for 4 weeks.Treatment and control group 2 received tacrolimus 0.1% ointment twice one day for 8 weeks. Results After the treatment of 8 weeks,total efifciencies of the treatment group, control group 1 and control group 2 were 86.11%,62.96% and34.38% respectively. No serious adverse reaction was observed in these three groups. Statistically signiifcant difference was observed between the overall effective rate of treatment group and control group(P<0.05).Conclusion ALA-PDT and tacrolimus 0.1% ointment are both safe and effective in the treatment of rosacea,which can also improve patients’ quality of life.关键词
ALA-PDT/他克莫司/玫瑰痤疮/联合/疗效观察Key words
5-aminolevulinic acid-photodynamic therapy/tacrolimus/rosacea/combined/observation of therapeutic effect分类
医药卫生引用本文复制引用
杨宪鲁,王海燕,雷旭光,苏芳,董岩,孙玉鲁..ALA-PDT联合0.1%他克莫司软膏治疗玫瑰痤疮疗效观察与分析[J].中国美容医学,2016,25(2):55-57,3.