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RNA 干扰在肿瘤治疗中的研究进展

袁慎俊 胡卫 陈涛

中国全科医学2016,Vol.19Issue(12):1367-1370,1374,5.
中国全科医学2016,Vol.19Issue(12):1367-1370,1374,5.DOI:10.3969/j.issn.1007-9572.2016.12.002

RNA 干扰在肿瘤治疗中的研究进展

Progress of RNAi Technology for Cancer Therapy

袁慎俊 1胡卫 1陈涛1

作者信息

  • 1. 443002 湖北省宜昌市,三峡大学医学院
  • 折叠

摘要

Abstract

Malignant tumors are a major threat to human health,and at present the primary types of treatment such as surgery,radiation and chemotherapy do not have a good effect. This text introduced the mechanism of RNA interference(RNAi) and the application of RNAi technology in cancer therapy,described drug delivery methods of RNAi in the therapy,RNAi -induced off - target effects and immune response. Although problems still exist in the treatment by RNAi,RNAi - based cancer therapy may be a new method for the clinical treatment of cancer by further research.

关键词

RNA 干扰/肿瘤治疗方案/脱靶效应/免疫反应

Key words

RNA interference/Antineoplastic protocols/Off - target effects/Immune response

分类

医药卫生

引用本文复制引用

袁慎俊,胡卫,陈涛..RNA 干扰在肿瘤治疗中的研究进展[J].中国全科医学,2016,19(12):1367-1370,1374,5.

基金项目

国家自然科学基金资助项目 ()

中国全科医学

OA北大核心CSTPCD

1007-9572

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