中国医药科学2016，Vol.6Issue(3)：171-174,4.
血清LXA4与降钙素原在急性阑尾炎患者中的动态监测
Dynamic monitoring of serum LXA4 and procalcitonin in patients with acute appendicitis
朱克华 1张福2
作者信息
- 1. 辽宁省建昌县黑山科中心医院普外科，辽宁建昌125311
- 2. 河北省秦皇岛工人医院普外科，河北秦皇岛066299
- 折叠
摘要
Abstract
Objective To analyze effects of LXA4 and PCT on the diagnosis and prognosis of patients with acute appendicitis by dynamic monitoring of peripheral blood lipoxin A4 (LXA4) and procalcitonin (PCT) levels. Methods 120 patients with acute appendicitis who were admitted to our hospital from March 2011 to June 2015 were selected.LXA4 and PCT levels before operation and the second day after operation (11-35h) were monitored by Enzyme-linked immunosorbent assay (ELISA) and they were analyzed and compared. Results In 120 patients with acute appendicitis,there were 35 cases of simple appendicitis,47 cases of suppurative appendicitis and 38 cases of perforated appendicitis or gangrenous appendicitis according to the surgery or (and) pathological diagnosis results. The levels of the serum LXA4 before operation of 120 patients with acute appendicitis before the operation were all higher than those after operation (P < 0.05).Preoperative serum LXA4 levels of the suppurative,perforated and gangrenous appendicitis groups were higher than that of the simple appendicitis group (P<0.01) and the difference was statistically significant.The difference between simple appendicitis group and the suppurative, perforated and gangrenous appendicitis groups had no statistical significance (P > 0.05).Preoperative serum PCT levels of the simple,suppurative,perforated and gangrenous appendicitis groups were all higher than those before operation (P<0.05). Preoperative serum PCT levels of the suppurative, perforated and gangrenous appendicitis groups were higher than that of the simple appendicitis group (P < 0.01).And the difference was statistically significant.Postoperative serum PCT levels between suppurative,perforated and gangrenous appendicitis groups and the simple appendicitis group had no statistical significance (P > 0.05). Conclusion Monitoring of serum LXA4 and PCT levels of acute appendicitis patients has certain guiding significance in diagnosis, operation assessment and the prognosis recovery of acute appendicitis.关键词
急性阑尾炎/化脓性阑尾炎/诊断/脂氧素A4/降钙素原Key words
Acute appendicitis/Suppurative appendicitis/Diagnosis/Lipoxin A4/Procalcitonin分类
医药卫生引用本文复制引用
朱克华,张福..血清LXA4与降钙素原在急性阑尾炎患者中的动态监测[J].中国医药科学,2016,6(3):171-174,4.
