转化医学杂志2016，Vol.5Issue(2)：74-77,4.DOI:10.3969/j.issn.2095-3097.2016.02.003
彩色多普勒超声及超声造影在乳腺癌新辅助化疗疗效评估中的价值
The value of color Doppler ultrasound and contrast-enhanced ultrasound in assessment of neoadjuvant chemotherapy in breast cancer
摘要
Abstract
Objective To investigate the value of color Doppler ultrasound and contrast-en-hanced ultrasound evaluation of the efficacy of neoadjuvant chemotherapy ( neoadjuvant chemothera-py, NAC) in breast cancer. Methods This study included 60 breast cancer patients who received NAC and surgical treatment between January 2014 to June 2015. Tumor sizes, blood flow grading, resistance index ( RI ) and other related indicators were recorded before and after chemotherapy using color Doppler ultrasound. Of which 26 patients were examined by contrast-enhanced ultrasound and recorded relevant parameters, which including arrival time, time to peak and peak intensity, the efficacy of NAC was assessed according to the change of before and after chemotherapy. Results The maximum lesion diameter, shape, border, surrounding halo zone, change internal echo, blood flow grading and RI values after NAC had significant changes than before ( P<0. 05) . The AT, TTP and PI after NAC had significant difference than before ( P<0. 05) . Conclusion Contrast-enhanced ul-trasound can detect changes in the indicators NAC before and after chemotherapy in breast cancer cases and accurately assess the efficacy of NAC.关键词
乳腺癌/新辅助化疗/彩色多普勒超声/超声造影Key words
Breast cancer/Neoadjuvant chemotherapy ( NAC)/Color Doppler ultrasound/Contrast-enhanced ultrasound分类
医药卫生引用本文复制引用
董丽楠,宋海霞,李碧丽..彩色多普勒超声及超声造影在乳腺癌新辅助化疗疗效评估中的价值[J].转化医学杂志,2016,5(2):74-77,4.基金项目
内蒙古自然科学基金面上项目(2015MS08110) （2015MS08110）
