中国现代中药2016,Vol.18Issue(2):156-160,163,6.DOI:10.13313/j.issn.1673-4890.2016.2.006
岗梅根、茎体外抗呼吸道病毒的作用比较研究
Comparative Study on Effect of Ilex asprella Root and Stem against Respiratory Viruses
摘要
Abstract
Objective:To observe and compare the inhibitory effect of Ilex asprella root aqueous extract and I.asprella stem aqueous extract on several respiroviruses,in order to provide references for expansion of I.asprella’s medicinal parts.Methods:MDCK,A549,HEL and LLC-MK2 cell were infected with influenza virus type A FM1 strain,RSV, rhinovirus type 1 4,adenovirus type 3,parainfluenza virus type 3 separately.The inhibitory effect of I.asprella root aqueous extract and I.asprella stem aqueous extract on influenza virus type A FM1 strain was observed by using chicken hemagglutination method.And CPE was used to observe the inhibitory effect of I.asprella root aqueous extract and I.asprella stem aqueous extract on RSV,rhinovirus type 1 4,adenovirus type 3,parainfluenza virus type 3.Results:At the nontoxic concentration,I.asprella root aqueous extract can inhibit influenza virus type A FM1 strain,RSV and parainfluenza virus type 3,while I.asprella stem aqueous extract only inhibit adenovirus type 3 and RSV.Conclusion:Both I.asprella root aqueous extract and I.asprella stem aqueous extract can inhibit some of respiratory viruses in vitro.The inhibitory effect of I.asprella root aqueous extract on respiratory viruses in vitro is better than that of I.asprella stem aqueous extract.关键词
岗梅根/岗梅茎/体外抗病毒/呼吸道病毒Key words
Ilex asprella root/Ilex asprella stem/anti-respiratory in vitro/respiratory viruses引用本文复制引用
陈炜璇,韩正洲,仰铁锤,马庆,詹若挺,谈英,陈蔚文,张奉学..岗梅根、茎体外抗呼吸道病毒的作用比较研究[J].中国现代中药,2016,18(2):156-160,163,6.基金项目
[基金项目]“十二五”科技重大专项(2012ZX09201-201-001);广东省科技计划项目 ()