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小分子RNA在子宫内膜异位症中的研究进展

马志华 高尚风

中国妇幼健康研究2016,Vol.27Issue(4):546-549,4.
中国妇幼健康研究2016,Vol.27Issue(4):546-549,4.DOI:10.3969/j.issn.1673-5293.2016.04.043

小分子RNA在子宫内膜异位症中的研究进展

Research progress of micro-RNA in endometriosis

马志华 1高尚风1

作者信息

  • 1. 西安交通大学第一附属医院妇产科,陕西西安710061
  • 折叠

摘要

Abstract

Micro-RNA (miRNA) is a kind of small endogenous non-coding RNA molecule, which plays an important role in regulating the incidence and development of endometriosis (EMS) .It is correlated with EMS associated infertility and canceration of EMS as well. With stable expression and relatively high sensitivity and specificity, miRNAs are rarely degraded by RNA and can secrete into blood. According to difference in miRNAs expression in EMS, it is presumed that EMS could be diagnosed by detecting miRNAs in blood, and that EMS targeted therapy could be performed with miRNAs antagonists and analogies.

关键词

子宫内膜异位症/小分子RNA/诊断/靶向治疗

Key words

endometriosis (EMS)/micro-RNA (miRNA)/diagnosis/targeted therapy

分类

医药卫生

引用本文复制引用

马志华,高尚风..小分子RNA在子宫内膜异位症中的研究进展[J].中国妇幼健康研究,2016,27(4):546-549,4.

中国妇幼健康研究

1673-5293

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