临床与病理杂志2016，Vol.36Issue(3)：285-289,5.DOI:10.3978/j.issn.2095-6959.2016.03.014
高尿酸血症对肾脏损害的研究进展
The research progress of hyperuricemia induces kidney diseases
摘要
Abstract
In recent years, a large number of epidemiological studies indicated that hyperuricemia can cause kidney diseases. hTe main pathophysiological mechanisms of these harmful effects caused by uric acid are endothelial dysfunction, activation of renin-angiotensin system, release of pro-inlfammatory factors and increased oxidative stress. So it may have important clinical implications for assisting in the cognition process of asymptomatic hyperuricemia allowing for early renal function intervention. hTis article simply reviewed the cause of how hyperuricemia formed and the mechanism of renal impairment.关键词
高尿酸血症/肾损伤/发病机制Key words
hyperuricemia/kidney diseases/pathogenesis引用本文复制引用
陈芳(综述),李素梅(审校)..高尿酸血症对肾脏损害的研究进展[J].临床与病理杂志,2016,36(3):285-289,5.基金项目
安徽省卫生厅医学科研课题计划(13zc017)。@@@@This work was supported by Medical Scientiifc Research Project of Anhui Provincial Health Offce (13zc017), P. R. China （13zc017）
