临床与病理杂志2016，Vol.36Issue(3)：327-330,4.DOI:10.3978/j.issn.2095-6959.2016.03.021
中枢神经系统损伤疾病的坏死性凋亡机制研究进展
The advanced research of necroptosis and the central nervous system injured diseases
杨海玉(综述) 1刘勇(审校)2
作者信息
- 1. 江西省人民医院 临床医学研究所，南昌 330006
- 2. 江西省人民医院 病理科，南昌 330006
- 折叠
摘要
Abstract
Necroptosis is a kind of programmed necrosis that is newly discovered and regulated by RIP1 and RIP3 atfer the activation of death receptor signaling pathway, and it can be speciifc inhibited by necrostatin-1, a small compound. The present study confirmed that necroptosis was involved mechanisms of a variety of central nervous system (CNS) damages, and intervention of necroptosis signaling pathways had certain protective effects on CNS injuries caused by many factors. Further study the regulatory mechanism of necroptosis is expected to be provided more potential new targets for the treatment of the CNS injured diseases.关键词
坏死性凋亡/中枢神经系统/损伤Key words
necroptosis/central nervous system/injury引用本文复制引用
杨海玉(综述),刘勇(审校)..中枢神经系统损伤疾病的坏死性凋亡机制研究进展[J].临床与病理杂志,2016,36(3):327-330,4.
