哈尔滨商业大学学报（自然科学版）2016，Vol.32Issue(2)：146-149,153,5.
秦皮乙素对荷瘤小鼠红细胞免疫功能的影响
Effect of Aesculetin on function of erythrocyte membrane in tumor-bearing mice
摘要
Abstract
To study the effect of Aesculetin on the function of erythrocyte membrane in S180 tumor-bearing mice and its erythrocyte immune mechanism of antitumor the model of S180 tumor-bearing mice was obtained by transplanting S180 tumor cell line in vivo.Erythrocytic immunity was assayed by red blood cell immune complexes rosette.The tumor-bearing mice red cell membrane sialic acid content, activities of Na+, K+-ATPase and Ca2+, Mg2+-ATPase were tested by spectrophotometric method.Western Blot was used to determine the content of Band3 protein.Results indicate that Aesculetin can enhance the ability of S180 tumor-bearing mice red cell immune adhesion of tumor cells, increase the content of saliva acid and Band3 protein in erythrocyte membrane and improve the activities of Na+, K+-ATPase and Ca2+, Mg2+ -ATPase.Aesculetin may improve the function of erythrocyte membrane in S180 tumor bearing mice, improve the stability of the membrane and enhance the ability of erythrocyte immune adherence to tumor cells, so as to fulfill its antitumor effect.关键词
秦皮乙素/S180荷瘤小鼠/红细胞免疫/抗肿瘤Key words
Aesculetin/S180 tumor-bearing mice/erythrocyte immune/antitumor分类
医药卫生引用本文复制引用
许冉达,邵天宇,贾绍华..秦皮乙素对荷瘤小鼠红细胞免疫功能的影响[J].哈尔滨商业大学学报（自然科学版）,2016,32(2):146-149,153,5.基金项目
哈尔滨商业大学研究生创新科研项目(YJSCX2014-336HSD) （YJSCX2014-336HSD）
哈尔滨商业大学博士科研启动项目(14LG01) （14LG01）
