中国当代医药2016,Vol.23Issue(3):83-85,3.
改进西咪替丁胶囊溶出度的测定方法
Detection method of improvement the Cimetidine Capsule dissolution rate
秦松 1张蓓2
作者信息
- 1. 河南省焦作市食品药品检验所,河南焦作 454000
- 2. 焦作大学,河南焦作 454000
- 折叠
摘要
Abstract
Objective To explore the detection method of improvement the Cimetidine Capsule dissolution rate. Meth-ods HPLC was used to determine the dissolutionrate of Cimetidine Capsule.The measurement results of improved method were compared with Chinese Pharmacopeia. Results On the concentrationscale from 0.02 to 0.2 mg/ml,the peak area had nice linear relationship with concentration,and r,recovery rate and RSD were respectively 0.9998,99.82% and 0.33% (n=6). Conclusion The improved method has advantages of more accurate,more exact,more scientific and strong specificity.关键词
西咪替丁胶囊/高效液相色谱法/溶出度Key words
Cimetidine Capsule/HPLC/Dissolution rate分类
医药卫生引用本文复制引用
秦松,张蓓..改进西咪替丁胶囊溶出度的测定方法[J].中国当代医药,2016,23(3):83-85,3.