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改进西咪替丁胶囊溶出度的测定方法

秦松 张蓓

中国当代医药2016,Vol.23Issue(3):83-85,3.
中国当代医药2016,Vol.23Issue(3):83-85,3.

改进西咪替丁胶囊溶出度的测定方法

Detection method of improvement the Cimetidine Capsule dissolution rate

秦松 1张蓓2

作者信息

  • 1. 河南省焦作市食品药品检验所,河南焦作 454000
  • 2. 焦作大学,河南焦作 454000
  • 折叠

摘要

Abstract

Objective To explore the detection method of improvement the Cimetidine Capsule dissolution rate. Meth-ods HPLC was used to determine the dissolutionrate of Cimetidine Capsule.The measurement results of improved method were compared with Chinese Pharmacopeia. Results On the concentrationscale from 0.02 to 0.2 mg/ml,the peak area had nice linear relationship with concentration,and r,recovery rate and RSD were respectively 0.9998,99.82% and 0.33% (n=6). Conclusion The improved method has advantages of more accurate,more exact,more scientific and strong specificity.

关键词

西咪替丁胶囊/高效液相色谱法/溶出度

Key words

Cimetidine Capsule/HPLC/Dissolution rate

分类

医药卫生

引用本文复制引用

秦松,张蓓..改进西咪替丁胶囊溶出度的测定方法[J].中国当代医药,2016,23(3):83-85,3.

中国当代医药

1674-4721

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