中国当代医药2016，Vol.23Issue(3)：93-95,3.
中医药对膀胱癌术后灌注化疗减毒增效的临床研究
Clinical study of traditional Chinese medicine on toxicity reducing and ef-ficacy enhancing of infusion chemotherapy after bladder cancer surgery
摘要
Abstract
Objective To explore the clinical effect of traditional Chinese medicine (TCM) on toxicity reducing and ef-ficacy enhancing of infusion chemotherapy after bladder cancer surgery. Methods From March 2013 to March 2015,60 early-stage superficial bladder cancer patients undergone transurethral resection of the prostate (TURP) were admitted into our hospital and divided into experimental group and control group by the random number table.In the control group,only chemotherapy drug from bladder infusion was used,while in the experimental group,Chinese decoction based on syndrome differentiation and treatment was added.The comprehensive scoring of symptoms,occurrence of side effect, and postoperative recurrence rate before and after treatment between two groups were compared. Results The compre-hensive scoring of symptoms after therapy in both groups was much less than that before treatment respectively(P﹤0.05). The comprehensive scoring of symptoms after therapy in the experimental group was lower than that in the control group (P﹤0.05).There were no statistical differences in side effects including fever,gastrointestinal side effect,bone mar-row suppression,hepatic and renal functions damaging,rash,hair loss,or mild electrocardiogram change (P>0.05).The du-ration of above mentioned side effects in the experimental group was greatly shorter in comparison with that in the con-trol group (P﹤0.05).In the control group,recurrence rate one or three years after surgery was 36.67%(11/30) and 46.67%(14/30) respectively,while in the experimental group,it was 13.33%(4/30) and 26.67%(8/30) respectively,which dis-played statistical differences (P﹤0.05). Conclusion TCMˊs effect of toxicity reducing and efficacy enhancing on infusion chemotherapy after bladder cancer surgery is remarkable in clinic with short duration of toxic and side effects.关键词
膀胱癌/中医药/灌注化疗/减毒增效Key words
Bladder cancer/Traditional Chinese medicine/Infusion chemotherapy/Toxicity reducing and efficacy en-hancing分类
医药卫生引用本文复制引用
罗松涛,栽美英,韩立,王明杰..中医药对膀胱癌术后灌注化疗减毒增效的临床研究[J].中国当代医药,2016,23(3):93-95,3.基金项目
泸州医学院-泸州医学院附属中医医院联合科研基金 （）
