检验医学与临床2016,Vol.13Issue(8):1016-1017,1019,3.DOI:10.3969/j.issn.1672-9455.2016.08.003
宜宾地区健康儿童血清胱抑素C参考区间的建立
Establishment of reference intervals for children serum cystatin C in Yibin area
摘要
Abstract
Objective To establish the reference intervals for serum cystatin C (Cys C) in healthy children in Yibin area .Methods A total of 1 163 healthy children (616 boys and 547 girls) aged from 2 d to 12 years old were enrolled and divided into 5 groups according to the age .The fasting venous blood specimens were collected and centri‐fuged .Then serum Cys C level was measured by using the enhanced immunoturbidimetric assay .The reference inter‐vals for various age groups were established by using the normal distribution methods .Results The serum Cys C level had no statistical difference between boys and girls in the same age group (P>0 .05) .The serum Cys C level had no difference between the 3-6 years old group and the 7-12 years old group (P>0 .05) .The serum Cys C level in children within 1 year old showed the downtrend with the month old increase(Y =1 .46 -0 .047X ,r= -0 .947) . Thereference intervals for the groups of < 29 d old ,29 d - < 1 year old ,1 -2 years old and ≥3 years old were 1 .18-2 .28 ,0 .61-1 .79 ,0 .52-1 .22 ,0 .44-1 .10 mg/L respectively .Conclusion The reference intervals for serum Cys C among healthy Han children in Yibin area is established ,which has an important significance for early evalua‐ting the renal function damage .关键词
健康人群/半胱氨酸蛋白酶抑制剂/参考区间Key words
healthy individual/cysteine proteinase inhibitor/reference interval引用本文复制引用
江翠,逯心敏,胡孝彬..宜宾地区健康儿童血清胱抑素C参考区间的建立[J].检验医学与临床,2016,13(8):1016-1017,1019,3.基金项目
国家高技术研究发展计划(863计划)资助项目(2011AA02A111)。 ()