检验医学与临床2016，Vol.13Issue(8)：1022-1024,3.DOI:10.3969/j.issn.1672-9455.2016.08.006
血清谷氨酸氨基转移酶与高尿酸血症的相关性分析
Analysis of correlation between serum alanine aminotransferase and hyperuricemia occurrence
摘要
Abstract
gf Objective To analyze the relationship between serum alanine aminotransferase (ALT) and hype‐ruricemia occurrence .Methods Sixty‐nine patients with hyperuricemia were selected as the observation group and 60 healthy people were chosen as the control group;serum levels of ALT and serum uric acid (SUA) were detected in the two groups ,and the levels of serum inflammatory factors (TNF‐α,CRP ,IL‐6) and fat factors(FFA ,APN) were detected in the observation group .The occurrence rate of ALT increase in the two groups were performed statistics . The levels of serum inflammatory factors and the fat factors in the observation group were compared among different ALT increased levels .Results The occurrence rate of ALT increase and the ALT level in the observation group were higher than those in the control group (P<0 .05) .In the SUA level aiming at the patients of the observation group , the ALT severe elevated group>moderately elevated group>mildly elevated group>non‐elevated group (P<0 .05);in the serum TNF‐α,IL‐6 ,CRP and FFA levels ,ALT severe elevated group>moderately elevated group>mildly el‐evated group>non‐elevated group (P<0 .05);in the serum APN level ,severely elevated group<moderately elevated group<mild elevated group<non‐elevated group (P<0 .05) .Conclusion The elevation of serum ALT is closely re‐lated to the occurrence of hyperuricemia ,and the serum ALT level has the same varying trend with level of SUA and has interaction .The mechanism may be related to the changes of serum inflammatory factors and fat factors .关键词
高尿酸血症/谷氨酸氨基转移酶/尿酸Key words
hyperuricemia/serum alanine aminotransferase/serum uric acid引用本文复制引用
刘颖,马凤云,陆敏华..血清谷氨酸氨基转移酶与高尿酸血症的相关性分析[J].检验医学与临床,2016,13(8):1022-1024,3.基金项目
广东省自然科学基金资助项目（S2013010011540）。 （）
