检验医学与临床2016，Vol.13Issue(8)：1027-1029,3.DOI:10.3969/j.issn.1672-9455.2016.08.008
超声引导连续锁骨下臂丛阻滞术后镇痛效果及对炎性反应的影响
Clinical study of ultrasound-guided continuous infraclavicular brachial plexus blocks for postoperative analgesia and in-flammatory response
摘要
Abstract
Objective To compare the postoperative analgesic effect of ultrasound‐guided continuous infracla‐vicular brachial plexus blocks by the coracoid process bypass approach and sufentanil intravenous analgesia in the pa‐tients with upper limb multiple fractures both upper limbs and their influence on the expression of inflammatory cyto‐kines (IL‐6 and IL‐10) .Methods Eighty ASA I patients with upper limb multiple fractures were selected and ran‐domly divided into 2 groups .The treatment group(n=40) adopted the ultrasound‐guided continuous infraclavicular brachial plexus blocks by the coracoid process bypass approach for conducting postoperative analgesia ,while the con‐trol group(n=40) adopted the sufentanil by patient‐control intravenous analgesia .The heart rate(HR) ,mean arterial blood pressure(MAP) were recorded before anesthesia(T1) and at postoperative 6(T2) ,12(T3) ,24(T4) ,48 h(T5) in the two groups .The peripheral plasma IL‐6 and IL‐10 levels at T1-T5 were detected .The rest and active move‐ment VAS scores at T2 -T5 were recorded .The cases number of nausea and vomiting were recorded Results HR and MAP at T3 and T4 in the control group were higher than those in the treatment group (P<0 .05) .The rest VAS score at T3 and T4 and the active VAS score at T3 ,T4 and T5 in the treatment group were decreased compared with the control group (P<0 .05) .In the intra‐group comparison ,plasma levels of IL‐6 and IL‐10 at T2 -T5 were in‐creased in different degrees compared with those at T1(P<0 .05);the plasma levels of IL‐6 at T3 and T4 in the treatment group was lower than those in the control group (P<0 .05) .Plasma levels of IL‐10 at T3 and T4 in the treatment group were higher than those in the control group (P<0 .05) .The incidence rate of nausea and vomiting in the treatment group was lower than that in the control group (P<0 .05) .Conclusion Ultrasound‐guided continuous infraclavicular brachial plexus blocks is safe ,reliable and easy way for postoperative analgesia ,which is beneficial to the balance of cytokines and reduction of the complications after operations .关键词
超声引导/连续锁骨下臂丛阻滞/术后镇痛/炎性反应Key words
ultrasound-guided/continuous infraclavicular brachial plexus blocks/postoperative analgesia/inflammatory response引用本文复制引用
陈立成,罗富荣,廖荣宗,龚琴,冯舒韵,范伟锋..超声引导连续锁骨下臂丛阻滞术后镇痛效果及对炎性反应的影响[J].检验医学与临床,2016,13(8):1027-1029,3.基金项目
广东省佛山市医学科研基金项目（2015198）。 （）
